Does PHENYTOIN Cause Porphyria? 6 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 6 reports of Porphyria have been filed in association with PHENYTOIN (PHENYTOIN SODIUM). This represents 0.0% of all adverse event reports for PHENYTOIN.
6
Reports of Porphyria with PHENYTOIN
0.0%
of all PHENYTOIN reports
2
Deaths
5
Hospitalizations
How Dangerous Is Porphyria From PHENYTOIN?
Of the 6 reports, 2 (33.3%) resulted in death, 5 (83.3%) required hospitalization, and 3 (50.0%) were considered life-threatening.
Is Porphyria Listed in the Official Label?
Yes, Porphyria is listed as a known adverse reaction in the official FDA drug label for PHENYTOIN.
What Other Side Effects Does PHENYTOIN Cause?
Drug ineffective (2,753)
Seizure (1,907)
Toxicity to various agents (1,248)
Drug hypersensitivity (898)
Off label use (852)
Drug interaction (772)
Drug reaction with eosinophilia and systemic symptoms (673)
Status epilepticus (544)
Fall (436)
Rash (414)
What Other Drugs Cause Porphyria?
HEMIN (14)
GIVOSIRAN (11)
ACETAMINOPHEN (8)
METHOTREXATE (7)
TESTOSTERONE (7)
TRAMADOL (7)
ALPRAZOLAM (5)
LEFLUNOMIDE (5)
NITISINONE (5)
RIBAVIRIN (5)
Which PHENYTOIN Alternatives Have Lower Porphyria Risk?
PHENYTOIN vs PHLEUM PRATENSE POLLEN
PHENYTOIN vs PHLOROGLUCINOL
PHENYTOIN vs PHLOROGLUCINOL\1,3,5-TRIMETHOXYBENZENE
PHENYTOIN vs PHOLCODINE
PHENYTOIN vs PHOSPHORUS