Porphyria: Which Medications Cause It? (204 Reports Across 11 Drugs)
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Porphyria has been reported as an adverse event with 11 different drugs in the FDA's FAERS database, with 204 total reports. 8 of these reports resulted in death.The drugs most commonly associated with Porphyria are HEMIN, GIVOSIRAN, and ACETAMINOPHEN.
204
Total Reports
11
Drugs Involved
8
Deaths
79
Hospitalizations
42.9 yrs
Average Patient Age
69.9% / 30.1%
Female / Male
Which Drugs Cause Porphyria Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| HEMIN | 14 | 3.9% | 1 | 8 | 0 |
| GIVOSIRAN | 11 | 0.9% | 0 | 8 | 0 |
| ACETAMINOPHEN | 8 | 0.0% | 0 | 4 | 0 |
| METHOTREXATE | 7 | 0.0% | 0 | 0 | 0 |
| TESTOSTERONE | 7 | 0.0% | 0 | 5 | 0 |
| TRAMADOL | 7 | 0.0% | 0 | 4 | 0 |
| PHENYTOIN | 6 | 0.0% | 2 | 5 | 3 |
| ALPRAZOLAM | 5 | 0.0% | 0 | 2 | 0 |
| LEFLUNOMIDE | 5 | 0.0% | 0 | 0 | 0 |
| NITISINONE | 5 | 0.7% | 0 | 5 | 0 |
| RIBAVIRIN | 5 | 0.0% | 0 | 4 | 0 |