Does PIRFENIDONE Cause Nephrolithiasis? 123 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 123 reports of Nephrolithiasis have been filed in association with PIRFENIDONE (PIRFENIDONE). This represents 0.3% of all adverse event reports for PIRFENIDONE.
123
Reports of Nephrolithiasis with PIRFENIDONE
0.3%
of all PIRFENIDONE reports
14
Deaths
66
Hospitalizations
How Dangerous Is Nephrolithiasis From PIRFENIDONE?
Of the 123 reports, 14 (11.4%) resulted in death, 66 (53.7%) required hospitalization.
Is Nephrolithiasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PIRFENIDONE. However, 123 reports have been filed with the FAERS database.
What Other Side Effects Does PIRFENIDONE Cause?
Death (7,221)
Nausea (4,944)
Fatigue (3,597)
Decreased appetite (3,126)
Diarrhoea (3,026)
Dyspnoea (2,526)
Weight decreased (2,113)
Dizziness (2,027)
Rash (1,982)
Cough (1,692)
What Other Drugs Cause Nephrolithiasis?
ADALIMUMAB (2,416)
ETANERCEPT (1,292)
INFLIXIMAB (981)
METHOTREXATE (979)
ABATACEPT (788)
TOPIRAMATE (768)
CERTOLIZUMAB PEGOL (735)
RITUXIMAB (709)
TOFACITINIB (699)
SODIUM OXYBATE (698)
Which PIRFENIDONE Alternatives Have Lower Nephrolithiasis Risk?
PIRFENIDONE vs PIRIBEDIL
PIRFENIDONE vs PIRITRAMIDE
PIRFENIDONE vs PIROXICAM
PIRFENIDONE vs PIRTOBRUTINIB
PIRFENIDONE vs PIT VIPER IMMUNE GLOBULIN ANTIVENIN