Does PONATINIB Cause Cardiac dysfunction? 11 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 11 reports of Cardiac dysfunction have been filed in association with PONATINIB (Iclusig). This represents 0.1% of all adverse event reports for PONATINIB.
11
Reports of Cardiac dysfunction with PONATINIB
0.1%
of all PONATINIB reports
2
Deaths
4
Hospitalizations
How Dangerous Is Cardiac dysfunction From PONATINIB?
Of the 11 reports, 2 (18.2%) resulted in death, 4 (36.4%) required hospitalization, and 2 (18.2%) were considered life-threatening.
Is Cardiac dysfunction Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PONATINIB. However, 11 reports have been filed with the FAERS database.
What Other Side Effects Does PONATINIB Cause?
Death (1,735)
Off label use (1,071)
Product dose omission issue (817)
Fatigue (687)
Rash (639)
Headache (553)
Pyrexia (542)
Nausea (466)
Hospitalisation (459)
Constipation (435)
What Other Drugs Cause Cardiac dysfunction?
SACUBITRIL\VALSARTAN (523)
TRASTUZUMAB (359)
CYCLOPHOSPHAMIDE (172)
DOXORUBICIN (142)
ADALIMUMAB (118)
AMLODIPINE (113)
EPIRUBICIN (111)
PERTUZUMAB (111)
PACLITAXEL (90)
PEMBROLIZUMAB (81)
Which PONATINIB Alternatives Have Lower Cardiac dysfunction Risk?
PONATINIB vs PONATINIB\PONATINIB
PONATINIB vs PONESIMOD
PONATINIB vs PORACTANT ALFA
PONATINIB vs PORFIMER
PONATINIB vs POSACONAZOLE