Cardiac dysfunction: Which Medications Cause It? (3,299 Reports Across 276 Drugs)
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Cardiac dysfunction has been reported as an adverse event with 276 different drugs in the FDA's FAERS database, with 3,299 total reports. 426 of these reports resulted in death.The drugs most commonly associated with Cardiac dysfunction are SACUBITRIL\VALSARTAN, TRASTUZUMAB, and CYCLOPHOSPHAMIDE.
3,299
Total Reports
276
Drugs Involved
426
Deaths
1,341
Hospitalizations
57.7 yrs
Average Patient Age
51.7% / 48.3%
Female / Male
Which Drugs Cause Cardiac dysfunction Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| SACUBITRIL\VALSARTAN | 523 | 0.5% | 28 | 160 | 31 |
| TRASTUZUMAB | 359 | 0.8% | 29 | 47 | 15 |
| CYCLOPHOSPHAMIDE | 172 | 0.1% | 32 | 46 | 19 |
| DOXORUBICIN | 142 | 0.2% | 12 | 39 | 11 |
| ADALIMUMAB | 118 | 0.0% | 7 | 65 | 7 |
| AMLODIPINE | 113 | 0.2% | 12 | 98 | 70 |
| EPIRUBICIN | 111 | 0.7% | 2 | 26 | 10 |
| PERTUZUMAB | 111 | 0.5% | 4 | 21 | 5 |
| PACLITAXEL | 90 | 0.1% | 8 | 13 | 10 |
| PEMBROLIZUMAB | 81 | 0.1% | 10 | 39 | 13 |
| DEXAMETHASONE | 72 | 0.1% | 13 | 36 | 12 |
| RITUXIMAB | 69 | 0.0% | 9 | 18 | 6 |
| VINCRISTINE | 63 | 0.1% | 10 | 21 | 1 |
| METFORMIN | 62 | 0.1% | 1 | 40 | 24 |
| PREDNISONE | 60 | 0.0% | 9 | 21 | 5 |
| METOPROLOL | 58 | 0.1% | 0 | 42 | 13 |
| LENALIDOMIDE | 55 | 0.0% | 13 | 18 | 5 |
| BEVACIZUMAB | 54 | 0.1% | 4 | 16 | 3 |
| ATORVASTATIN | 52 | 0.1% | 3 | 37 | 4 |
| LENVATINIB | 52 | 0.2% | 4 | 33 | 1 |