Does PROCARBAZINE Cause Malignant transformation? 31 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 31 reports of Malignant transformation have been filed in association with PROCARBAZINE (Matulane). This represents 0.5% of all adverse event reports for PROCARBAZINE.
31
Reports of Malignant transformation with PROCARBAZINE
0.5%
of all PROCARBAZINE reports
24
Deaths
2
Hospitalizations
How Dangerous Is Malignant transformation From PROCARBAZINE?
Of the 31 reports, 24 (77.4%) resulted in death, 2 (6.5%) required hospitalization, and 2 (6.5%) were considered life-threatening.
Is Malignant transformation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PROCARBAZINE. However, 31 reports have been filed with the FAERS database.
What Other Side Effects Does PROCARBAZINE Cause?
Nausea (1,029)
Fatigue (890)
Vomiting (375)
Neutropenia (311)
Off label use (301)
Constipation (274)
Platelet count decreased (246)
White blood cell count decreased (229)
Headache (222)
Acute myeloid leukaemia (195)
What Other Drugs Cause Malignant transformation?
OSIMERTINIB (109)
ETOPOSIDE (108)
MELPHALAN (95)
CYTARABINE (91)
CARMUSTINE (88)
CYCLOPHOSPHAMIDE (73)
PREDNISONE (69)
GEFITINIB (67)
VINCRISTINE (66)
DOXORUBICIN (61)
Which PROCARBAZINE Alternatives Have Lower Malignant transformation Risk?
PROCARBAZINE vs PROCHLORPERAZINE
PROCARBAZINE vs PROCHLORPERAZINE EDISYLATE
PROCARBAZINE vs PROCRIT
PROCARBAZINE vs PROCYCLIDINE
PROCARBAZINE vs PROGESTERONE