PROPYLTHIOURACIL for Hyperthyroidism: Side Effects & Safety Data
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There are 373 adverse event reports in the FDA FAERS database where PROPYLTHIOURACIL was used for Hyperthyroidism.
Most Reported Side Effects for PROPYLTHIOURACIL
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Drug ineffective | 121 | 12.7% | 6 | 86 |
| Foetal exposure during pregnancy | 110 | 11.6% | 3 | 26 |
| Anti-neutrophil cytoplasmic antibody positive vasculitis | 81 | 8.5% | 7 | 35 |
| Exposure during pregnancy | 75 | 7.9% | 0 | 20 |
| Hyperthyroidism | 58 | 6.1% | 2 | 35 |
| Off label use | 54 | 5.7% | 0 | 31 |
| Maternal exposure during pregnancy | 50 | 5.3% | 0 | 18 |
| Agranulocytosis | 42 | 4.4% | 5 | 27 |
| Vasculitis | 41 | 4.3% | 1 | 32 |
| Premature baby | 38 | 4.0% | 1 | 14 |
| Neutropenia | 35 | 3.7% | 2 | 20 |
| Antineutrophil cytoplasmic antibody positive | 32 | 3.4% | 1 | 17 |
| Acute hepatic failure | 29 | 3.1% | 6 | 20 |
| Drug-induced liver injury | 26 | 2.7% | 2 | 12 |
| Thyrotoxic crisis | 26 | 2.7% | 7 | 20 |
Other Indications for PROPYLTHIOURACIL
Basedow's disease (138)
Product used for unknown indication (134)
Thyrotoxic crisis (112)
Graves' disease (92)
Secondary hyperthyroidism (11)
Foetal exposure during pregnancy (9)
Thyroid disorder (7)
Exposure during pregnancy (6)
Other Drugs Used for Hyperthyroidism
METHIMAZOLE (897)
CARBIMAZOLE (355)
LEVOTHYROXINE (287)
PROPRANOLOL (196)
PREDNISONE (107)
SODIUM PERCHLORATE (64)
TEPROTUMUMAB-TRBW (47)
POTASSIUM IODIDE (46)
CHOLESTYRAMINE (45)
HYDROCORTISONE (44)