Does PROPYLTHIOURACIL Cause Agranulocytosis? 42 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 42 reports of Agranulocytosis have been filed in association with PROPYLTHIOURACIL (Propylthiouracil). This represents 4.4% of all adverse event reports for PROPYLTHIOURACIL.
42
Reports of Agranulocytosis with PROPYLTHIOURACIL
4.4%
of all PROPYLTHIOURACIL reports
5
Deaths
27
Hospitalizations
How Dangerous Is Agranulocytosis From PROPYLTHIOURACIL?
Of the 42 reports, 5 (11.9%) resulted in death, 27 (64.3%) required hospitalization, and 5 (11.9%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
Yes, Agranulocytosis is listed as a known adverse reaction in the official FDA drug label for PROPYLTHIOURACIL.
What Other Side Effects Does PROPYLTHIOURACIL Cause?
Drug ineffective (121)
Foetal exposure during pregnancy (110)
Anti-neutrophil cytoplasmic antibody positive vasculitis (81)
Exposure during pregnancy (75)
Hyperthyroidism (58)
Off label use (54)
Maternal exposure during pregnancy (50)
Vasculitis (41)
Premature baby (38)
Neutropenia (35)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which PROPYLTHIOURACIL Alternatives Have Lower Agranulocytosis Risk?
PROPYLTHIOURACIL vs PROTAMINE
PROPYLTHIOURACIL vs PROTHIPENDYL
PROPYLTHIOURACIL vs PROTIONAMIDE
PROPYLTHIOURACIL vs PROTONIX
PROPYLTHIOURACIL vs PROTOPIC