Does CLOZAPINE Cause Agranulocytosis? 1,766 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,766 reports of Agranulocytosis have been filed in association with CLOZAPINE (CLOZAPINE). This represents 1.9% of all adverse event reports for CLOZAPINE.
1,766
Reports of Agranulocytosis with CLOZAPINE
1.9%
of all CLOZAPINE reports
111
Deaths
552
Hospitalizations
How Dangerous Is Agranulocytosis From CLOZAPINE?
Of the 1,766 reports, 111 (6.3%) resulted in death, 552 (31.3%) required hospitalization, and 505 (28.6%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
Yes, Agranulocytosis is listed as a known adverse reaction in the official FDA drug label for CLOZAPINE.
What Other Side Effects Does CLOZAPINE Cause?
Neutropenia (18,981)
Hospitalisation (12,144)
Death (9,500)
Schizophrenia (3,991)
White blood cell count decreased (3,454)
Off label use (3,192)
Neutrophil count increased (3,125)
Drug ineffective (3,105)
Neutrophilia (3,105)
White blood cell count increased (2,988)
What Other Drugs Cause Agranulocytosis?
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
CARBOPLATIN (407)
Which CLOZAPINE Alternatives Have Lower Agranulocytosis Risk?
CLOZAPINE vs CLOZARIL
CLOZAPINE vs COAGULATION FACTOR IX HUMAN\COAGULATION FACTOR VII HUMAN\COAGULATION FACTOR X HUMAN\PROTEIN C\PROTEIN S HUMAN\PROTHROMBIN
CLOZAPINE vs COAGULATION FACTOR IX HUMAN\COAGULATION FACTOR VII HUMAN\COAGULATION FACTOR X HUMAN\PROTHROMBIN
CLOZAPINE vs COAGULATION FACTOR IX RECOMBINANT HUMAN
CLOZAPINE vs COAGULATION FACTOR IX RECOMBINANT HUMAN\ISOPROPYL ALCOHOL