Does SULFAMETHOXAZOLE\TRIMETHOPRIM Cause Agranulocytosis? 797 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 797 reports of Agranulocytosis have been filed in association with SULFAMETHOXAZOLE\TRIMETHOPRIM. This represents 2.1% of all adverse event reports for SULFAMETHOXAZOLE\TRIMETHOPRIM.
797
Reports of Agranulocytosis with SULFAMETHOXAZOLE\TRIMETHOPRIM
2.1%
of all SULFAMETHOXAZOLE\TRIMETHOPRIM reports
40
Deaths
625
Hospitalizations
How Dangerous Is Agranulocytosis From SULFAMETHOXAZOLE\TRIMETHOPRIM?
Of the 797 reports, 40 (5.0%) resulted in death, 625 (78.4%) required hospitalization, and 152 (19.1%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SULFAMETHOXAZOLE\TRIMETHOPRIM. However, 797 reports have been filed with the FAERS database.
What Other Side Effects Does SULFAMETHOXAZOLE\TRIMETHOPRIM Cause?
Drug ineffective (4,868)
Rash (4,649)
Pyrexia (4,364)
Drug hypersensitivity (4,184)
Pruritus (3,483)
Dyspnoea (3,351)
Fatigue (3,229)
Off label use (3,078)
Pain (3,058)
Hypersensitivity (2,913)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
CARBOPLATIN (407)
Which SULFAMETHOXAZOLE\TRIMETHOPRIM Alternatives Have Lower Agranulocytosis Risk?
SULFAMETHOXAZOLE\TRIMETHOPRIM vs SULFANILAMIDE
SULFAMETHOXAZOLE\TRIMETHOPRIM vs SULFASALAZINE
SULFAMETHOXAZOLE\TRIMETHOPRIM vs SULFATHIAZOLE
SULFAMETHOXAZOLE\TRIMETHOPRIM vs SULFISOMIDINE
SULFAMETHOXAZOLE\TRIMETHOPRIM vs SULFUR