Does CYCLOPHOSPHAMIDE Cause Agranulocytosis? 1,242 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,242 reports of Agranulocytosis have been filed in association with CYCLOPHOSPHAMIDE (Cyclophosphamide). This represents 1.0% of all adverse event reports for CYCLOPHOSPHAMIDE.
1,242
Reports of Agranulocytosis with CYCLOPHOSPHAMIDE
1.0%
of all CYCLOPHOSPHAMIDE reports
63
Deaths
438
Hospitalizations
How Dangerous Is Agranulocytosis From CYCLOPHOSPHAMIDE?
Of the 1,242 reports, 63 (5.1%) resulted in death, 438 (35.3%) required hospitalization, and 182 (14.7%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CYCLOPHOSPHAMIDE. However, 1,242 reports have been filed with the FAERS database.
What Other Side Effects Does CYCLOPHOSPHAMIDE Cause?
Off label use (12,578)
Febrile neutropenia (11,318)
Drug ineffective (8,142)
Neutropenia (7,352)
Disease progression (7,100)
Pyrexia (6,126)
Product use in unapproved indication (5,750)
Thrombocytopenia (4,669)
Pneumonia (4,595)
Nausea (4,561)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
CARBOPLATIN (407)
Which CYCLOPHOSPHAMIDE Alternatives Have Lower Agranulocytosis Risk?
CYCLOPHOSPHAMIDE vs CYCLOPHOSPHAMIDE FOR , USP
CYCLOPHOSPHAMIDE vs CYCLOPHOSPHAMIDE\DOXORUBICIN\PREDNISONE\RITUXIMAB\VINCRISTINE
CYCLOPHOSPHAMIDE vs CYCLOPHOSPHAMIDE\DOXORUBICIN\PREDNISONE\VINCRISTINE
CYCLOPHOSPHAMIDE vs CYCLOSERINE
CYCLOPHOSPHAMIDE vs CYCLOSPORINE