PYRIMETHAMINE for Malaria prophylaxis: Side Effects & Safety Data
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There are 5 adverse event reports in the FDA FAERS database where PYRIMETHAMINE was used for Malaria prophylaxis.
Most Reported Side Effects for PYRIMETHAMINE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 126 | 14.9% | 12 | 31 |
| Nausea | 121 | 14.3% | 1 | 30 |
| Vomiting | 73 | 8.6% | 4 | 17 |
| Neutropenia | 72 | 8.5% | 0 | 38 |
| Pancytopenia | 66 | 7.8% | 5 | 50 |
| Rash | 53 | 6.3% | 0 | 12 |
| Headache | 45 | 5.3% | 0 | 12 |
| Death | 39 | 4.6% | 39 | 9 |
| Thrombocytopenia | 34 | 4.0% | 2 | 25 |
| Dizziness | 33 | 3.9% | 0 | 5 |
| Drug ineffective | 33 | 3.9% | 10 | 17 |
| Pyrexia | 33 | 3.9% | 8 | 20 |
| Diarrhoea | 32 | 3.8% | 4 | 19 |
| Acute kidney injury | 31 | 3.7% | 1 | 18 |
| Bone marrow failure | 30 | 3.6% | 6 | 28 |
Other Indications for PYRIMETHAMINE
Toxoplasmosis (318)
Cerebral toxoplasmosis (141)
Eye infection toxoplasmal (106)
Product used for unknown indication (60)
Hiv infection (39)
Congenital toxoplasmosis (19)
Toxoplasmosis prophylaxis (17)
Evidence based treatment (10)
Encephalitis (7)
Bacterial endophthalmitis (6)
Other Drugs Used for Malaria prophylaxis
ATOVAQUONE\PROGUANIL (327)
DOXYCYCLINE (198)
MEFLOQUINE (123)
ATOVAQUONE (31)
DOXYCYCLINE HYCLATE (29)
CHLOROQUINE (26)
PROGUANIL (21)
MALARONE (20)
SULFAMETHOXAZOLE\TRIMETHOPRIM (8)
PYRIMETHAMINE\SULFADOXINE (6)