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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Malaria prophylaxis: Which Medications Are Safest? (43 Drugs Compared)

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43 medications are used for Malaria prophylaxis, with 823 combined adverse event reports. The most reported drugs for Malaria prophylaxis are ATOVAQUONE\PROGUANIL and DOXYCYCLINE.

823
Total Reports
43
Drugs Used

All Medications for Malaria prophylaxis Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
ATOVAQUONE\PROGUANIL - 327 13 190 1.8%
DOXYCYCLINE Doxycycline 198 1,653 5,618 9.3%
MEFLOQUINE Mefloquine Hydrochloride 123 49 96 16.0%
ATOVAQUONE Atovaquone 31 366 1,110 16.1%
DOXYCYCLINE HYCLATE Doxycycline Hyclate 29 1,164 1,650 19.1%
CHLOROQUINE Chloroquinum Phos. 26 217 521 14.2%
PROGUANIL - 21 2 7 5.6%
MALARONE - 20 0 12 N/A
SULFAMETHOXAZOLE\TRIMETHOPRIM - 8 5,777 19,426 14.9%
PYRIMETHAMINE\SULFADOXINE - 6 3 10 10.7%
HYDROXYCHLOROQUINE HYDROXYCHLOROQUINE SULFATE 5 6,506 16,905 9.8%
PYRIMETHAMINE Pyrimethamine 5 90 322 10.7%
SULFADOXINE - 5 0 2 N/A

View all 43 drugs →

Most Reported Drugs for Malaria prophylaxis

#1 most reported
#2 most reported
#3 most reported