REGORAFENIB for Ewing's sarcoma: Side Effects & Safety Data
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There are 13 adverse event reports in the FDA FAERS database where REGORAFENIB was used for Ewing's sarcoma.
Most Reported Side Effects for REGORAFENIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 1,906 | 20.2% | 244 | 702 |
| Fatigue | 1,530 | 16.2% | 168 | 556 |
| Palmar-plantar erythrodysaesthesia syndrome | 1,230 | 13.0% | 201 | 297 |
| Diarrhoea | 1,221 | 12.9% | 174 | 418 |
| Decreased appetite | 941 | 10.0% | 146 | 408 |
| Asthenia | 825 | 8.7% | 159 | 373 |
| Death | 813 | 8.6% | 810 | 166 |
| Dysphonia | 702 | 7.4% | 57 | 232 |
| Nausea | 688 | 7.3% | 86 | 312 |
| Pain in extremity | 686 | 7.3% | 31 | 197 |
| Pyrexia | 626 | 6.6% | 85 | 422 |
| Hypertension | 606 | 6.4% | 77 | 201 |
| Weight decreased | 574 | 6.1% | 82 | 217 |
| Vomiting | 477 | 5.1% | 64 | 267 |
| Pain | 473 | 5.0% | 53 | 169 |
Other Indications for REGORAFENIB
Colon cancer (1,699)
Colorectal cancer (1,313)
Colorectal cancer metastatic (1,234)
Hepatocellular carcinoma (1,050)
Rectal cancer (505)
Gastrointestinal stromal tumour (473)
Product used for unknown indication (253)
Hepatic cancer (252)
Metastases to liver (252)
Colon cancer metastatic (205)
Other Drugs Used for Ewing's sarcoma
DOXORUBICIN (1,047)
VINCRISTINE (993)
ETOPOSIDE (978)
IFOSFAMIDE (937)
CYCLOPHOSPHAMIDE (721)
DACTINOMYCIN (282)
IRINOTECAN (155)
TEMOZOLOMIDE (148)
MESNA (88)
CABOZANTINIB S-MALATE (84)