REGORAFENIB for Soft tissue sarcoma: Side Effects & Safety Data
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There are 40 adverse event reports in the FDA FAERS database where REGORAFENIB was used for Soft tissue sarcoma.
Most Reported Side Effects for REGORAFENIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 1,906 | 20.2% | 244 | 702 |
| Fatigue | 1,530 | 16.2% | 168 | 556 |
| Palmar-plantar erythrodysaesthesia syndrome | 1,230 | 13.0% | 201 | 297 |
| Diarrhoea | 1,221 | 12.9% | 174 | 418 |
| Decreased appetite | 941 | 10.0% | 146 | 408 |
| Asthenia | 825 | 8.7% | 159 | 373 |
| Death | 813 | 8.6% | 810 | 166 |
| Dysphonia | 702 | 7.4% | 57 | 232 |
| Nausea | 688 | 7.3% | 86 | 312 |
| Pain in extremity | 686 | 7.3% | 31 | 197 |
| Pyrexia | 626 | 6.6% | 85 | 422 |
| Hypertension | 606 | 6.4% | 77 | 201 |
| Weight decreased | 574 | 6.1% | 82 | 217 |
| Vomiting | 477 | 5.1% | 64 | 267 |
| Pain | 473 | 5.0% | 53 | 169 |
Other Indications for REGORAFENIB
Colon cancer (1,699)
Colorectal cancer (1,313)
Colorectal cancer metastatic (1,234)
Hepatocellular carcinoma (1,050)
Rectal cancer (505)
Gastrointestinal stromal tumour (473)
Product used for unknown indication (253)
Hepatic cancer (252)
Metastases to liver (252)
Colon cancer metastatic (205)
Other Drugs Used for Soft tissue sarcoma
PAZOPANIB (1,400)
DOXORUBICIN (302)
TAZEMETOSTAT HYDROBROMIDE (298)
IFOSFAMIDE (237)
CABOZANTINIB S-MALATE (192)
TRABECTEDIN (183)
NIVOLUMAB (156)
OLARATUMAB (156)
IMATINIB (124)
SUNITINIB MALATE (123)