Does RUXOLITINIB Cause Nephrolithiasis? 266 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 266 reports of Nephrolithiasis have been filed in association with RUXOLITINIB (OPZELURA). This represents 0.4% of all adverse event reports for RUXOLITINIB.
266
Reports of Nephrolithiasis with RUXOLITINIB
0.4%
of all RUXOLITINIB reports
26
Deaths
143
Hospitalizations
How Dangerous Is Nephrolithiasis From RUXOLITINIB?
Of the 266 reports, 26 (9.8%) resulted in death, 143 (53.8%) required hospitalization, and 10 (3.8%) were considered life-threatening.
Is Nephrolithiasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for RUXOLITINIB. However, 266 reports have been filed with the FAERS database.
What Other Side Effects Does RUXOLITINIB Cause?
Off label use (12,492)
Death (6,561)
Fatigue (5,663)
Anaemia (3,593)
Haemoglobin decreased (3,297)
Platelet count decreased (3,028)
Diarrhoea (2,531)
Asthenia (2,529)
Dizziness (2,398)
Pneumonia (2,343)
What Other Drugs Cause Nephrolithiasis?
ADALIMUMAB (2,416)
ETANERCEPT (1,292)
INFLIXIMAB (981)
METHOTREXATE (979)
ABATACEPT (788)
TOPIRAMATE (768)
CERTOLIZUMAB PEGOL (735)
RITUXIMAB (709)
TOFACITINIB (699)
SODIUM OXYBATE (698)
Which RUXOLITINIB Alternatives Have Lower Nephrolithiasis Risk?
RUXOLITINIB vs SABRIL
RUXOLITINIB vs SACCHAROMYCES CEREVISIAE
RUXOLITINIB vs SACITUZUMAB GOVITECAN
RUXOLITINIB vs SACITUZUMAB GOVITECAN-HZIY
RUXOLITINIB vs SACROSIDASE