Does SILTUXIMAB Cause Cytokine release syndrome? 26 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 26 reports of Cytokine release syndrome have been filed in association with SILTUXIMAB (Sylvant). This represents 5.5% of all adverse event reports for SILTUXIMAB.
26
Reports of Cytokine release syndrome with SILTUXIMAB
5.5%
of all SILTUXIMAB reports
18
Deaths
9
Hospitalizations
How Dangerous Is Cytokine release syndrome From SILTUXIMAB?
Of the 26 reports, 18 (69.2%) resulted in death, 9 (34.6%) required hospitalization, and 3 (11.5%) were considered life-threatening.
Is Cytokine release syndrome Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SILTUXIMAB. However, 26 reports have been filed with the FAERS database.
What Other Side Effects Does SILTUXIMAB Cause?
Off label use (96)
Drug ineffective (72)
Disease progression (32)
Immune effector cell-associated neurotoxicity syndrome (28)
Death (27)
Hypertension (24)
Product use in unapproved indication (24)
Drug effective for unapproved indication (23)
Cataract (19)
Condition aggravated (19)
What Other Drugs Cause Cytokine release syndrome?
AXICABTAGENE CILOLEUCEL (4,140)
CYCLOPHOSPHAMIDE (2,263)
TISAGENLECLEUCEL (1,660)
FLUDARABINE (1,458)
RITUXIMAB (1,404)
BLINATUMOMAB (952)
DEXAMETHASONE (853)
DOXORUBICIN (850)
BREXUCABTAGENE AUTOLEUCEL (827)
VINCRISTINE (771)
Which SILTUXIMAB Alternatives Have Lower Cytokine release syndrome Risk?
SILTUXIMAB vs SILVER SULFADIAZINE
SILTUXIMAB vs SIMEPREVIR
SILTUXIMAB vs SIMPONI
SILTUXIMAB vs SIMVASTATIN
SILTUXIMAB vs SINGULAIR