Does SIROLIMUS Cause Hyponatraemia? 28 Reports in FDA Database

Q: Does SIROLIMUS cause Hyponatraemia?

28 reports of Hyponatraemia have been filed with the FDA for SIROLIMUS, representing 0.3% of all SIROLIMUS adverse event reports.

Q: How dangerous is Hyponatraemia from SIROLIMUS?

Of 28 reports, 10 (35.7%) resulted in death and 16 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 28 reports of Hyponatraemia have been filed in association with SIROLIMUS (sirolimus). This represents 0.3% of all adverse event reports for SIROLIMUS.

Reports of Hyponatraemia with SIROLIMUS

0.3%

of all SIROLIMUS reports

Deaths

Hospitalizations

How Dangerous Is Hyponatraemia From SIROLIMUS?

Of the 28 reports, 10 (35.7%) resulted in death, 16 (57.1%) required hospitalization, and 8 (28.6%) were considered life-threatening.

Is Hyponatraemia Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for SIROLIMUS. However, 28 reports have been filed with the FAERS database.

What Other Side Effects Does SIROLIMUS Cause?

Off label use (1,960) Drug ineffective (1,005) Product use in unapproved indication (984) Transplant rejection (698) Pneumonia (599) Product use issue (506) Alopecia (491) Acne (482) Transplant dysfunction (468) Condition aggravated (433)

What Other Drugs Cause Hyponatraemia?

FUROSEMIDE (3,127) HYDROCHLOROTHIAZIDE (2,138) OMEPRAZOLE (1,635) LANSOPRAZOLE (1,416) SERTRALINE (1,332) RAMIPRIL (1,178) SPIRONOLACTONE (1,166) PANTOPRAZOLE (1,134) INDAPAMIDE (976) AMLODIPINE (879)

Which SIROLIMUS Alternatives Have Lower Hyponatraemia Risk?

SIROLIMUS vs SIRUKUMAB SIROLIMUS vs SITAGLIPTIN SIROLIMUS vs SOAP SIROLIMUS vs SODIUM SIROLIMUS vs SODIUM BICARBONATE

SIROLIMUS Full Profile All Hyponatraemia Reports All Drugs Causing Hyponatraemia SIROLIMUS Demographics