Does SIROLIMUS Cause Pancytopenia? 79 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 79 reports of Pancytopenia have been filed in association with SIROLIMUS (sirolimus). This represents 0.7% of all adverse event reports for SIROLIMUS.
79
Reports of Pancytopenia with SIROLIMUS
0.7%
of all SIROLIMUS reports
17
Deaths
49
Hospitalizations
How Dangerous Is Pancytopenia From SIROLIMUS?
Of the 79 reports, 17 (21.5%) resulted in death, 49 (62.0%) required hospitalization, and 8 (10.1%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
Yes, Pancytopenia is listed as a known adverse reaction in the official FDA drug label for SIROLIMUS.
What Other Side Effects Does SIROLIMUS Cause?
Off label use (1,960)
Drug ineffective (1,005)
Product use in unapproved indication (984)
Transplant rejection (698)
Pneumonia (599)
Product use issue (506)
Alopecia (491)
Acne (482)
Transplant dysfunction (468)
Condition aggravated (433)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which SIROLIMUS Alternatives Have Lower Pancytopenia Risk?
SIROLIMUS vs SIRUKUMAB
SIROLIMUS vs SITAGLIPTIN
SIROLIMUS vs SOAP
SIROLIMUS vs SODIUM
SIROLIMUS vs SODIUM BICARBONATE