Does SOFOSBUVIR Cause Hepatic encephalopathy? 360 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 360 reports of Hepatic encephalopathy have been filed in association with SOFOSBUVIR (Epclusa). This represents 2.1% of all adverse event reports for SOFOSBUVIR.
360
Reports of Hepatic encephalopathy with SOFOSBUVIR
2.1%
of all SOFOSBUVIR reports
89
Deaths
229
Hospitalizations
How Dangerous Is Hepatic encephalopathy From SOFOSBUVIR?
Of the 360 reports, 89 (24.7%) resulted in death, 229 (63.6%) required hospitalization, and 23 (6.4%) were considered life-threatening.
Is Hepatic encephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SOFOSBUVIR. However, 360 reports have been filed with the FAERS database.
What Other Side Effects Does SOFOSBUVIR Cause?
Fatigue (2,004)
Drug ineffective (1,833)
Hepatitis c (1,662)
Headache (1,417)
Nausea (1,211)
Off label use (1,184)
Anaemia (1,065)
Insomnia (940)
Hepatocellular carcinoma (877)
Treatment failure (806)
What Other Drugs Cause Hepatic encephalopathy?
ACETAMINOPHEN (562)
RIBAVIRIN (512)
LENVATINIB (502)
RIFAXIMIN (462)
BEVACIZUMAB (210)
LEDIPASVIR\SOFOSBUVIR (180)
ATEZOLIZUMAB (178)
SORAFENIB (169)
DACLATASVIR (165)
FUROSEMIDE (130)
Which SOFOSBUVIR Alternatives Have Lower Hepatic encephalopathy Risk?
SOFOSBUVIR vs SOFOSBUVIR\VELPATASVIR
SOFOSBUVIR vs SOFOSBUVIR\VELPATASVIR\VOXILAPREVIR
SOFOSBUVIR vs SOLIFENACIN
SOFOSBUVIR vs SOLIRIS
SOFOSBUVIR vs SOLOSTAR