Hepatic encephalopathy: Which Medications Cause It? (6,462 Reports Across 424 Drugs)
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Hepatic encephalopathy has been reported as an adverse event with 424 different drugs in the FDA's FAERS database, with 6,462 total reports. 1,815 of these reports resulted in death.The drugs most commonly associated with Hepatic encephalopathy are ACETAMINOPHEN, RIBAVIRIN, and LENVATINIB.
6,462
Total Reports
424
Drugs Involved
1,815
Deaths
4,737
Hospitalizations
56.9 yrs
Average Patient Age
43.8% / 56.2%
Female / Male
Which Drugs Cause Hepatic encephalopathy Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| ACETAMINOPHEN | 562 | 0.4% | 165 | 492 | 156 |
| RIBAVIRIN | 512 | 1.2% | 134 | 329 | 33 |
| LENVATINIB | 502 | 1.5% | 76 | 432 | 17 |
| RIFAXIMIN | 462 | 3.3% | 93 | 347 | 8 |
| SOFOSBUVIR | 360 | 2.1% | 89 | 229 | 23 |
| BEVACIZUMAB | 210 | 0.3% | 74 | 104 | 11 |
| LEDIPASVIR\SOFOSBUVIR | 180 | 0.8% | 48 | 122 | 9 |
| ATEZOLIZUMAB | 178 | 0.5% | 50 | 92 | 4 |
| SORAFENIB | 169 | 1.6% | 43 | 101 | 9 |
| DACLATASVIR | 165 | 3.0% | 48 | 101 | 11 |
| FUROSEMIDE | 130 | 0.3% | 18 | 99 | 17 |
| DASABUVIR | 108 | 2.7% | 27 | 86 | 14 |
| CYCLOPHOSPHAMIDE | 107 | 0.1% | 48 | 64 | 28 |
| OMBITASVIR\PARITAPREVIR\RITONAVIR | 106 | 2.3% | 28 | 83 | 16 |
| PREDNISONE | 105 | 0.1% | 39 | 78 | 38 |
| SPIRONOLACTONE | 104 | 0.5% | 14 | 83 | 12 |
| OXALIPLATIN | 103 | 0.2% | 33 | 45 | 26 |
| RIFAMPIN | 101 | 0.8% | 48 | 76 | 20 |
| RITUXIMAB | 101 | 0.1% | 52 | 68 | 26 |
| VINCRISTINE | 98 | 0.1% | 51 | 61 | 26 |