Does SOFOSBUVIR Cause Nephrolithiasis? 43 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 43 reports of Nephrolithiasis have been filed in association with SOFOSBUVIR (Epclusa). This represents 0.3% of all adverse event reports for SOFOSBUVIR.
43
Reports of Nephrolithiasis with SOFOSBUVIR
0.3%
of all SOFOSBUVIR reports
1
Deaths
27
Hospitalizations
How Dangerous Is Nephrolithiasis From SOFOSBUVIR?
Of the 43 reports, 1 (2.3%) resulted in death, 27 (62.8%) required hospitalization, and 1 (2.3%) were considered life-threatening.
Is Nephrolithiasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SOFOSBUVIR. However, 43 reports have been filed with the FAERS database.
What Other Side Effects Does SOFOSBUVIR Cause?
Fatigue (2,004)
Drug ineffective (1,833)
Hepatitis c (1,662)
Headache (1,417)
Nausea (1,211)
Off label use (1,184)
Anaemia (1,065)
Insomnia (940)
Hepatocellular carcinoma (877)
Treatment failure (806)
What Other Drugs Cause Nephrolithiasis?
ADALIMUMAB (2,416)
ETANERCEPT (1,292)
INFLIXIMAB (981)
METHOTREXATE (979)
ABATACEPT (788)
TOPIRAMATE (768)
CERTOLIZUMAB PEGOL (735)
RITUXIMAB (709)
TOFACITINIB (699)
SODIUM OXYBATE (698)
Which SOFOSBUVIR Alternatives Have Lower Nephrolithiasis Risk?
SOFOSBUVIR vs SOFOSBUVIR\VELPATASVIR
SOFOSBUVIR vs SOFOSBUVIR\VELPATASVIR\VOXILAPREVIR
SOFOSBUVIR vs SOLIFENACIN
SOFOSBUVIR vs SOLIRIS
SOFOSBUVIR vs SOLOSTAR