Does SOFOSBUVIR Cause Sepsis? 305 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 305 reports of Sepsis have been filed in association with SOFOSBUVIR (Epclusa). This represents 1.8% of all adverse event reports for SOFOSBUVIR.
305
Reports of Sepsis with SOFOSBUVIR
1.8%
of all SOFOSBUVIR reports
268
Deaths
63
Hospitalizations
How Dangerous Is Sepsis From SOFOSBUVIR?
Of the 305 reports, 268 (87.9%) resulted in death, 63 (20.7%) required hospitalization, and 11 (3.6%) were considered life-threatening.
Is Sepsis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SOFOSBUVIR. However, 305 reports have been filed with the FAERS database.
What Other Side Effects Does SOFOSBUVIR Cause?
Fatigue (2,004)
Drug ineffective (1,833)
Hepatitis c (1,662)
Headache (1,417)
Nausea (1,211)
Off label use (1,184)
Anaemia (1,065)
Insomnia (940)
Hepatocellular carcinoma (877)
Treatment failure (806)
What Other Drugs Cause Sepsis?
RITUXIMAB (4,043)
CYCLOPHOSPHAMIDE (4,041)
METHOTREXATE (3,933)
ADALIMUMAB (3,169)
DEXAMETHASONE (3,150)
LENALIDOMIDE (2,956)
VINCRISTINE (2,791)
DOXORUBICIN (2,740)
PREDNISONE (2,634)
PREDNISOLONE (2,281)
Which SOFOSBUVIR Alternatives Have Lower Sepsis Risk?
SOFOSBUVIR vs SOFOSBUVIR\VELPATASVIR
SOFOSBUVIR vs SOFOSBUVIR\VELPATASVIR\VOXILAPREVIR
SOFOSBUVIR vs SOLIFENACIN
SOFOSBUVIR vs SOLIRIS
SOFOSBUVIR vs SOLOSTAR