Does SORAFENIB Cause Pancytopenia? 159 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 159 reports of Pancytopenia have been filed in association with SORAFENIB (sorafenib). This represents 1.5% of all adverse event reports for SORAFENIB.
159
Reports of Pancytopenia with SORAFENIB
1.5%
of all SORAFENIB reports
13
Deaths
18
Hospitalizations
How Dangerous Is Pancytopenia From SORAFENIB?
Of the 159 reports, 13 (8.2%) resulted in death, 18 (11.3%) required hospitalization, and 7 (4.4%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SORAFENIB. However, 159 reports have been filed with the FAERS database.
What Other Side Effects Does SORAFENIB Cause?
Hepatocellular carcinoma (1,665)
Diarrhoea (1,611)
Off label use (1,587)
Fatigue (1,041)
Palmar-plantar erythrodysaesthesia syndrome (1,040)
Decreased appetite (906)
Death (904)
Asthenia (777)
Nausea (716)
Rash (613)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which SORAFENIB Alternatives Have Lower Pancytopenia Risk?
SORAFENIB vs SORGHUM HALEPENSE POLLEN
SORAFENIB vs SOTAGLIFLOZIN
SORAFENIB vs SOTALOL
SORAFENIB vs SOTATERCEPT
SORAFENIB vs SOTATERCEPT-CSRK