SPIRONOLACTONE for Hypertension: Side Effects & Safety Data
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There are 3,316 adverse event reports in the FDA FAERS database where SPIRONOLACTONE was used for Hypertension.
Most Reported Side Effects for SPIRONOLACTONE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Acute kidney injury | 3,273 | 15.6% | 256 | 2,669 |
| Hyperkalaemia | 2,518 | 12.0% | 154 | 1,871 |
| Hypotension | 1,583 | 7.5% | 131 | 1,081 |
| Dyspnoea | 1,468 | 7.0% | 62 | 1,043 |
| Drug ineffective | 1,379 | 6.6% | 65 | 642 |
| Hyponatraemia | 1,166 | 5.5% | 72 | 975 |
| Dizziness | 991 | 4.7% | 39 | 495 |
| Fatigue | 990 | 4.7% | 29 | 520 |
| Fall | 947 | 4.5% | 76 | 783 |
| Off label use | 899 | 4.3% | 53 | 357 |
| Dehydration | 897 | 4.3% | 74 | 722 |
| Cardiac failure | 781 | 3.7% | 146 | 548 |
| Headache | 723 | 3.4% | 12 | 418 |
| Condition aggravated | 714 | 3.4% | 84 | 461 |
| Drug interaction | 714 | 3.4% | 47 | 521 |
Other Indications for SPIRONOLACTONE
Product used for unknown indication (7,297)
Cardiac failure (1,622)
Ascites (387)
Diuretic therapy (375)
Cardiac failure congestive (348)
Acne (306)
Oedema (254)
Cardiac failure chronic (176)
Oedema peripheral (160)
Hidradenitis (145)
Other Drugs Used for Hypertension
AMLODIPINE (20,207)
LISINOPRIL (11,824)
RAMIPRIL (10,210)
VALSARTAN (8,956)
LOSARTAN (7,966)
FUROSEMIDE (7,490)
HYDROCHLOROTHIAZIDE (7,119)
METOPROLOL (5,918)
OLMESARTAN MEDOXOMIL (5,702)
BISOPROLOL (5,520)