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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Hypertension: Which Medications Are Safest? (1,579 Drugs Compared)

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1,579 medications are used for Hypertension, with 139,186 combined adverse event reports. The most reported drugs for Hypertension are AMLODIPINE and LISINOPRIL.

139,186
Total Reports
1,579
Drugs Used

All Medications for Hypertension Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
AMLODIPINE Olmesartan Medoxomil, Amlodipine and Hydrochlorothiazide 20,207 10,161 26,787 15.7%
LISINOPRIL Lisinopril 11,824 4,382 13,362 11.9%
RAMIPRIL Ramipril 10,210 3,786 17,747 11.5%
VALSARTAN valsartan 8,956 1,696 7,746 7.8%
LOSARTAN Losartan Potassium 7,966 2,034 7,032 9.3%
FUROSEMIDE Furosemide 7,490 6,131 30,446 11.8%
HYDROCHLOROTHIAZIDE Irbesartan and Hydrochlorothiazide 7,119 2,177 10,714 10.4%
METOPROLOL metoprolol succinate 5,918 6,575 15,925 15.9%
OLMESARTAN MEDOXOMIL OLMESARTAN MEDOXOMIL 5,702 283 6,564 2.4%
BISOPROLOL bisoprolol fumarate and hydrochlorothiazide 5,520 2,541 15,394 9.2%
IRBESARTAN Irbesartan 5,190 636 5,374 6.3%
HYDROCHLOROTHIAZIDE\VALSARTAN - 3,931 634 2,300 9.3%
SPIRONOLACTONE spironolactone 3,316 1,809 11,611 8.6%
ATENOLOL Atenolol and Chlorthalidone 3,261 1,722 5,024 14.0%
HYDROCHLOROTHIAZIDE\OLMESARTAN MEDOXOMIL - 3,244 95 3,369 1.6%
PERINDOPRIL - 2,994 565 4,472 7.1%
ENALAPRIL Enalapril maleate oral solution 2,892 711 3,919 9.2%
NEBIVOLOL nebivolol 2,516 455 2,586 7.2%
HYDRALAZINE Hydralazine Hydrochloride 2,412 716 2,694 12.1%
SACUBITRIL\VALSARTAN - 2,401 15,665 18,923 14.1%

View all 1,579 drugs →

Most Reported Drugs for Hypertension

#1 most reported
#2 most reported
#3 most reported