Does SPIRONOLACTONE Cause Lactic acidosis? 267 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 267 reports of Lactic acidosis have been filed in association with SPIRONOLACTONE (spironolactone). This represents 1.3% of all adverse event reports for SPIRONOLACTONE.
267
Reports of Lactic acidosis with SPIRONOLACTONE
1.3%
of all SPIRONOLACTONE reports
65
Deaths
112
Hospitalizations
How Dangerous Is Lactic acidosis From SPIRONOLACTONE?
Of the 267 reports, 65 (24.3%) resulted in death, 112 (41.9%) required hospitalization, and 129 (48.3%) were considered life-threatening.
Is Lactic acidosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SPIRONOLACTONE. However, 267 reports have been filed with the FAERS database.
What Other Side Effects Does SPIRONOLACTONE Cause?
Acute kidney injury (3,273)
Hyperkalaemia (2,518)
Hypotension (1,583)
Dyspnoea (1,468)
Drug ineffective (1,379)
Hyponatraemia (1,166)
Dizziness (991)
Fatigue (990)
Fall (947)
Off label use (899)
What Other Drugs Cause Lactic acidosis?
METFORMIN (16,316)
AMLODIPINE (886)
LINEZOLID (824)
FUROSEMIDE (698)
ACETAMINOPHEN (561)
METFORMIN\SITAGLIPTIN (557)
ALBUTEROL (467)
EMPAGLIFLOZIN (434)
RAMIPRIL (430)
BISOPROLOL (425)
Which SPIRONOLACTONE Alternatives Have Lower Lactic acidosis Risk?
SPIRONOLACTONE vs SPRYCEL
SPIRONOLACTONE vs STALEVO
SPIRONOLACTONE vs STANNOUS FLUORIDE
SPIRONOLACTONE vs STANOZOLOL
SPIRONOLACTONE vs STAVUDINE