Does SPIRONOLACTONE Cause Pneumothorax? 29 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 29 reports of Pneumothorax have been filed in association with SPIRONOLACTONE (spironolactone). This represents 0.1% of all adverse event reports for SPIRONOLACTONE.
29
Reports of Pneumothorax with SPIRONOLACTONE
0.1%
of all SPIRONOLACTONE reports
8
Deaths
22
Hospitalizations
How Dangerous Is Pneumothorax From SPIRONOLACTONE?
Of the 29 reports, 8 (27.6%) resulted in death, 22 (75.9%) required hospitalization, and 14 (48.3%) were considered life-threatening.
Is Pneumothorax Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SPIRONOLACTONE. However, 29 reports have been filed with the FAERS database.
What Other Side Effects Does SPIRONOLACTONE Cause?
Acute kidney injury (3,273)
Hyperkalaemia (2,518)
Hypotension (1,583)
Dyspnoea (1,468)
Drug ineffective (1,379)
Hyponatraemia (1,166)
Dizziness (991)
Fatigue (990)
Fall (947)
Off label use (899)
What Other Drugs Cause Pneumothorax?
ADALIMUMAB (530)
METHOTREXATE (380)
NINTEDANIB (310)
BEVACIZUMAB (293)
PREDNISONE (283)
ALBUTEROL (278)
PACLITAXEL (267)
PEMBROLIZUMAB (258)
NIVOLUMAB (254)
CARBOPLATIN (234)
Which SPIRONOLACTONE Alternatives Have Lower Pneumothorax Risk?
SPIRONOLACTONE vs SPRYCEL
SPIRONOLACTONE vs STALEVO
SPIRONOLACTONE vs STANNOUS FLUORIDE
SPIRONOLACTONE vs STANOZOLOL
SPIRONOLACTONE vs STAVUDINE