TARLATAMAB-DLLE for Off label use: Side Effects & Safety Data
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There are 9 adverse event reports in the FDA FAERS database where TARLATAMAB-DLLE was used for Off label use.
Most Reported Side Effects for TARLATAMAB-DLLE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Cytokine release syndrome | 274 | 34.1% | 36 | 103 |
| Immune effector cell-associated neurotoxicity syndrome | 127 | 15.8% | 15 | 51 |
| Off label use | 111 | 13.8% | 5 | 36 |
| Pyrexia | 75 | 9.3% | 4 | 26 |
| Small cell lung cancer | 66 | 8.2% | 22 | 19 |
| Death | 45 | 5.6% | 45 | 13 |
| Disease progression | 34 | 4.2% | 9 | 5 |
| Metastases to central nervous system | 28 | 3.5% | 0 | 6 |
| Decreased appetite | 23 | 2.9% | 1 | 8 |
| Dysgeusia | 22 | 2.7% | 1 | 2 |
| Fatigue | 22 | 2.7% | 1 | 5 |
| Headache | 20 | 2.5% | 1 | 6 |
| Ageusia | 17 | 2.1% | 0 | 1 |
| Hypotension | 17 | 2.1% | 1 | 6 |
| Taste disorder | 17 | 2.1% | 1 | 2 |
Other Indications for TARLATAMAB-DLLE
Small cell lung cancer (332)
Product used for unknown indication (284)
Small cell lung cancer extensive stage (127)
Small cell lung cancer recurrent (17)
Medullary thyroid cancer (13)
Small cell lung cancer metastatic (6)
Other Drugs Used for Off label use
LENALIDOMIDE (5,767)
ECULIZUMAB (3,550)
CERTOLIZUMAB PEGOL (2,256)
ABOBOTULINUMTOXINA (2,170)
LEVETIRACETAM (2,161)
APREMILAST (1,995)
PROPRANOLOL (1,576)
CETIRIZINE (1,416)
HUMAN IMMUNOGLOBULIN G (1,129)
THALIDOMIDE (1,033)