Does THIOGUANINE Cause Second primary malignancy? 21 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 21 reports of Second primary malignancy have been filed in association with THIOGUANINE (TABLOID). This represents 1.4% of all adverse event reports for THIOGUANINE.
21
Reports of Second primary malignancy with THIOGUANINE
1.4%
of all THIOGUANINE reports
10
Deaths
8
Hospitalizations
How Dangerous Is Second primary malignancy From THIOGUANINE?
Of the 21 reports, 10 (47.6%) resulted in death, 8 (38.1%) required hospitalization, and 2 (9.5%) were considered life-threatening.
Is Second primary malignancy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for THIOGUANINE. However, 21 reports have been filed with the FAERS database.
What Other Side Effects Does THIOGUANINE Cause?
Febrile neutropenia (470)
Haematotoxicity (174)
Off label use (94)
Pyrexia (80)
Sepsis (76)
Febrile bone marrow aplasia (73)
Neutropenia (69)
Thrombocytopenia (64)
Pancytopenia (61)
Death (49)
What Other Drugs Cause Second primary malignancy?
CYCLOPHOSPHAMIDE (1,247)
DOXORUBICIN (1,151)
VINCRISTINE (908)
IMATINIB (763)
PALBOCICLIB (658)
RITUXIMAB (646)
RUXOLITINIB (611)
ETOPOSIDE (573)
PREDNISONE (517)
OCTREOTIDE (496)
Which THIOGUANINE Alternatives Have Lower Second primary malignancy Risk?
THIOGUANINE vs THIOGUANINE ANHYDROUS
THIOGUANINE vs THIOPENTAL
THIOGUANINE vs THIORIDAZINE
THIOGUANINE vs THIOTEPA
THIOGUANINE vs THIOTHIXENE