Does THIOTEPA Cause Pancytopenia? 123 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 123 reports of Pancytopenia have been filed in association with THIOTEPA (Thiotepa). This represents 1.8% of all adverse event reports for THIOTEPA.
123
Reports of Pancytopenia with THIOTEPA
1.8%
of all THIOTEPA reports
39
Deaths
54
Hospitalizations
How Dangerous Is Pancytopenia From THIOTEPA?
Of the 123 reports, 39 (31.7%) resulted in death, 54 (43.9%) required hospitalization, and 33 (26.8%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for THIOTEPA. However, 123 reports have been filed with the FAERS database.
What Other Side Effects Does THIOTEPA Cause?
Off label use (762)
Febrile neutropenia (645)
Mucosal inflammation (616)
Cytomegalovirus infection (446)
Product use in unapproved indication (425)
Pyrexia (359)
Drug ineffective (358)
Acute graft versus host disease in skin (355)
Acute graft versus host disease (331)
Cytomegalovirus infection reactivation (325)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which THIOTEPA Alternatives Have Lower Pancytopenia Risk?
THIOTEPA vs THIOTHIXENE
THIOTEPA vs THROMBIN
THIOTEPA vs THROMBIN HUMAN
THIOTEPA vs THYMOCYTE IMMUNE GLOBULIN NOS
THIOTEPA vs THYMOGLOBULINE