TOBI for Off label use: Side Effects & Safety Data
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There are 12 adverse event reports in the FDA FAERS database where TOBI was used for Off label use.
Most Reported Side Effects for TOBI
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Death | 89 | 34.2% | 89 | 7 |
| Dyspnoea | 29 | 11.2% | 4 | 19 |
| Cystic fibrosis | 25 | 9.6% | 6 | 18 |
| Cough | 24 | 9.2% | 2 | 14 |
| Condition aggravated | 23 | 8.9% | 1 | 20 |
| Pneumonia | 20 | 7.7% | 3 | 18 |
| Pseudomonas infection | 19 | 7.3% | 3 | 12 |
| Malaise | 12 | 4.6% | 1 | 7 |
| Drug administered to patient of inappropriate age | 11 | 4.2% | 1 | 3 |
| Chronic obstructive pulmonary disease | 10 | 3.9% | 4 | 7 |
| Pyrexia | 10 | 3.9% | 1 | 7 |
| Chest discomfort | 9 | 3.5% | 0 | 5 |
| Productive cough | 9 | 3.5% | 1 | 6 |
| Bronchiectasis | 8 | 3.1% | 2 | 6 |
| Haemoptysis | 8 | 3.1% | 1 | 5 |
Other Indications for TOBI
Cystic fibrosis (97)
Bronchiectasis (52)
Pseudomonas infection (21)
Chronic obstructive pulmonary disease (17)
Pneumonia pseudomonal (12)
Bronchitis (5)
Other Drugs Used for Off label use
LENALIDOMIDE (5,767)
ECULIZUMAB (3,550)
CERTOLIZUMAB PEGOL (2,256)
ABOBOTULINUMTOXINA (2,170)
LEVETIRACETAM (2,161)
APREMILAST (1,995)
PROPRANOLOL (1,576)
CETIRIZINE (1,416)
HUMAN IMMUNOGLOBULIN G (1,129)
THALIDOMIDE (1,033)