TOCILIZUMAB for Off label use: Side Effects & Safety Data
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There are 63 adverse event reports in the FDA FAERS database where TOCILIZUMAB was used for Off label use.
Most Reported Side Effects for TOCILIZUMAB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Drug ineffective | 32,342 | 32.9% | 1,812 | 6,486 |
| Rheumatoid arthritis | 20,652 | 21.0% | 2,125 | 5,176 |
| Pain | 18,384 | 18.7% | 1,939 | 4,934 |
| Off label use | 18,256 | 18.5% | 3,347 | 5,844 |
| Arthralgia | 15,536 | 15.8% | 1,996 | 4,784 |
| Joint swelling | 14,831 | 15.1% | 2,093 | 4,081 |
| Fatigue | 13,802 | 14.0% | 2,217 | 4,295 |
| Rash | 12,327 | 12.5% | 2,019 | 4,046 |
| Drug intolerance | 11,952 | 12.1% | 1,587 | 3,341 |
| Contraindicated product administered | 11,547 | 11.7% | 1,409 | 3,008 |
| Arthropathy | 9,816 | 10.0% | 1,774 | 3,868 |
| Alopecia | 9,680 | 9.8% | 1,726 | 2,784 |
| Abdominal discomfort | 9,553 | 9.7% | 1,715 | 2,821 |
| Synovitis | 9,428 | 9.6% | 1,890 | 3,599 |
| Swelling | 9,420 | 9.6% | 1,850 | 2,910 |
Other Indications for TOCILIZUMAB
Rheumatoid arthritis (55,449)
Product used for unknown indication (21,090)
Giant cell arteritis (4,364)
Covid-19 (4,186)
Juvenile idiopathic arthritis (2,016)
Covid-19 pneumonia (1,583)
Still's disease (1,418)
Temporal arteritis (1,269)
Polymyalgia rheumatica (964)
Cytokine release syndrome (735)
Other Drugs Used for Off label use
LENALIDOMIDE (5,767)
ECULIZUMAB (3,550)
CERTOLIZUMAB PEGOL (2,256)
ABOBOTULINUMTOXINA (2,170)
LEVETIRACETAM (2,161)
APREMILAST (1,995)
PROPRANOLOL (1,576)
CETIRIZINE (1,416)
HUMAN IMMUNOGLOBULIN G (1,129)
THALIDOMIDE (1,033)