Does TOFACITINIB Cause Arthropathy? 7,054 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 7,054 reports of Arthropathy have been filed in association with TOFACITINIB (XELJANZ XR). This represents 4.5% of all adverse event reports for TOFACITINIB.
7,054
Reports of Arthropathy with TOFACITINIB
4.5%
of all TOFACITINIB reports
1,370
Deaths
2,800
Hospitalizations
How Dangerous Is Arthropathy From TOFACITINIB?
Of the 7,054 reports, 1,370 (19.4%) resulted in death, 2,800 (39.7%) required hospitalization, and 1,813 (25.7%) were considered life-threatening.
Is Arthropathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOFACITINIB. However, 7,054 reports have been filed with the FAERS database.
What Other Side Effects Does TOFACITINIB Cause?
Drug ineffective (30,382)
Pain (21,659)
Condition aggravated (16,925)
Arthralgia (15,640)
Fatigue (13,551)
Rheumatoid arthritis (12,277)
Off label use (11,736)
Headache (11,061)
Joint swelling (10,686)
Malaise (9,040)
What Other Drugs Cause Arthropathy?
ETANERCEPT (11,842)
ADALIMUMAB (11,670)
ABATACEPT (11,099)
METHOTREXATE (10,973)
TOCILIZUMAB (9,816)
LEFLUNOMIDE (9,277)
HYDROXYCHLOROQUINE (8,770)
RITUXIMAB (8,619)
INFLIXIMAB (8,410)
SULFASALAZINE (7,545)
Which TOFACITINIB Alternatives Have Lower Arthropathy Risk?
TOFACITINIB vs TOFERSEN
TOFACITINIB vs TOLNAFTATE
TOFACITINIB vs TOLODODEKIN ALFA
TOFACITINIB vs TOLTERODINE
TOFACITINIB vs TOLVAPTAN