Does TOFACITINIB Cause Gastrointestinal toxicity? 147 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 147 reports of Gastrointestinal toxicity have been filed in association with TOFACITINIB (XELJANZ XR). This represents 0.1% of all adverse event reports for TOFACITINIB.
147
Reports of Gastrointestinal toxicity with TOFACITINIB
0.1%
of all TOFACITINIB reports
15
Deaths
97
Hospitalizations
How Dangerous Is Gastrointestinal toxicity From TOFACITINIB?
Of the 147 reports, 15 (10.2%) resulted in death, 97 (66.0%) required hospitalization, and 15 (10.2%) were considered life-threatening.
Is Gastrointestinal toxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOFACITINIB. However, 147 reports have been filed with the FAERS database.
What Other Side Effects Does TOFACITINIB Cause?
Drug ineffective (30,382)
Pain (21,659)
Condition aggravated (16,925)
Arthralgia (15,640)
Fatigue (13,551)
Rheumatoid arthritis (12,277)
Off label use (11,736)
Headache (11,061)
Joint swelling (10,686)
Malaise (9,040)
What Other Drugs Cause Gastrointestinal toxicity?
CAPECITABINE (368)
FLUOROURACIL (358)
METHOTREXATE (345)
OXALIPLATIN (314)
CYCLOPHOSPHAMIDE (266)
RITUXIMAB (262)
CISPLATIN (251)
DOXORUBICIN (242)
IRINOTECAN (232)
CARBOPLATIN (231)
Which TOFACITINIB Alternatives Have Lower Gastrointestinal toxicity Risk?
TOFACITINIB vs TOFERSEN
TOFACITINIB vs TOLNAFTATE
TOFACITINIB vs TOLODODEKIN ALFA
TOFACITINIB vs TOLTERODINE
TOFACITINIB vs TOLVAPTAN