Does TOFACITINIB Cause Onychomadesis? 624 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 624 reports of Onychomadesis have been filed in association with TOFACITINIB (XELJANZ XR). This represents 0.4% of all adverse event reports for TOFACITINIB.
624
Reports of Onychomadesis with TOFACITINIB
0.4%
of all TOFACITINIB reports
436
Deaths
489
Hospitalizations
How Dangerous Is Onychomadesis From TOFACITINIB?
Of the 624 reports, 436 (69.9%) resulted in death, 489 (78.4%) required hospitalization, and 371 (59.5%) were considered life-threatening.
Is Onychomadesis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOFACITINIB. However, 624 reports have been filed with the FAERS database.
What Other Side Effects Does TOFACITINIB Cause?
Drug ineffective (30,382)
Pain (21,659)
Condition aggravated (16,925)
Arthralgia (15,640)
Fatigue (13,551)
Rheumatoid arthritis (12,277)
Off label use (11,736)
Headache (11,061)
Joint swelling (10,686)
Malaise (9,040)
What Other Drugs Cause Onychomadesis?
ADALIMUMAB (797)
METHOTREXATE (785)
RITUXIMAB (722)
TOCILIZUMAB (721)
ABATACEPT (703)
INFLIXIMAB (682)
SECUKINUMAB (678)
LEFLUNOMIDE (667)
GOLIMUMAB (660)
HYDROXYCHLOROQUINE (660)
Which TOFACITINIB Alternatives Have Lower Onychomadesis Risk?
TOFACITINIB vs TOFERSEN
TOFACITINIB vs TOLNAFTATE
TOFACITINIB vs TOLODODEKIN ALFA
TOFACITINIB vs TOLTERODINE
TOFACITINIB vs TOLVAPTAN