Does METHOTREXATE Cause Onychomadesis? 785 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 785 reports of Onychomadesis have been filed in association with METHOTREXATE (Methotrexate). This represents 0.3% of all adverse event reports for METHOTREXATE.
785
Reports of Onychomadesis with METHOTREXATE
0.3%
of all METHOTREXATE reports
556
Deaths
639
Hospitalizations
How Dangerous Is Onychomadesis From METHOTREXATE?
Of the 785 reports, 556 (70.8%) resulted in death, 639 (81.4%) required hospitalization, and 495 (63.1%) were considered life-threatening.
Is Onychomadesis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 785 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Onychomadesis?
ADALIMUMAB (797)
RITUXIMAB (722)
TOCILIZUMAB (721)
ABATACEPT (703)
INFLIXIMAB (682)
SECUKINUMAB (678)
LEFLUNOMIDE (667)
GOLIMUMAB (660)
HYDROXYCHLOROQUINE (660)
CERTOLIZUMAB PEGOL (654)
Which METHOTREXATE Alternatives Have Lower Onychomadesis Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA