Does TOFACITINIB Cause Pemphigus? 5,203 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 5,203 reports of Pemphigus have been filed in association with TOFACITINIB (XELJANZ XR). This represents 3.3% of all adverse event reports for TOFACITINIB.
5,203
Reports of Pemphigus with TOFACITINIB
3.3%
of all TOFACITINIB reports
1,469
Deaths
1,997
Hospitalizations
How Dangerous Is Pemphigus From TOFACITINIB?
Of the 5,203 reports, 1,469 (28.2%) resulted in death, 1,997 (38.4%) required hospitalization, and 1,806 (34.7%) were considered life-threatening.
Is Pemphigus Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOFACITINIB. However, 5,203 reports have been filed with the FAERS database.
What Other Side Effects Does TOFACITINIB Cause?
Drug ineffective (30,382)
Pain (21,659)
Condition aggravated (16,925)
Arthralgia (15,640)
Fatigue (13,551)
Rheumatoid arthritis (12,277)
Off label use (11,736)
Headache (11,061)
Joint swelling (10,686)
Malaise (9,040)
What Other Drugs Cause Pemphigus?
RITUXIMAB (8,574)
ABATACEPT (8,441)
METHOTREXATE (8,414)
PREDNISONE (8,260)
LEFLUNOMIDE (8,252)
TOCILIZUMAB (8,210)
FOLIC ACID (8,128)
ADALIMUMAB (8,079)
CETIRIZINE (8,063)
HYDROXYCHLOROQUINE (8,051)
Which TOFACITINIB Alternatives Have Lower Pemphigus Risk?
TOFACITINIB vs TOFERSEN
TOFACITINIB vs TOLNAFTATE
TOFACITINIB vs TOLODODEKIN ALFA
TOFACITINIB vs TOLTERODINE
TOFACITINIB vs TOLVAPTAN