Does TOFACITINIB Cause Porphyria acute? 192 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 192 reports of Porphyria acute have been filed in association with TOFACITINIB (XELJANZ XR). This represents 0.1% of all adverse event reports for TOFACITINIB.
192
Reports of Porphyria acute with TOFACITINIB
0.1%
of all TOFACITINIB reports
166
Deaths
180
Hospitalizations
How Dangerous Is Porphyria acute From TOFACITINIB?
Of the 192 reports, 166 (86.5%) resulted in death, 180 (93.8%) required hospitalization, and 181 (94.3%) were considered life-threatening.
Is Porphyria acute Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOFACITINIB. However, 192 reports have been filed with the FAERS database.
What Other Side Effects Does TOFACITINIB Cause?
Drug ineffective (30,382)
Pain (21,659)
Condition aggravated (16,925)
Arthralgia (15,640)
Fatigue (13,551)
Rheumatoid arthritis (12,277)
Off label use (11,736)
Headache (11,061)
Joint swelling (10,686)
Malaise (9,040)
What Other Drugs Cause Porphyria acute?
GIVOSIRAN (381)
RITUXIMAB (265)
DICLOFENAC (262)
LEFLUNOMIDE (249)
TOCILIZUMAB (243)
SECUKINUMAB (241)
METHOTREXATE (238)
ACETAMINOPHEN (237)
ADALIMUMAB (236)
PREDNISONE (227)
Which TOFACITINIB Alternatives Have Lower Porphyria acute Risk?
TOFACITINIB vs TOFERSEN
TOFACITINIB vs TOLNAFTATE
TOFACITINIB vs TOLODODEKIN ALFA
TOFACITINIB vs TOLTERODINE
TOFACITINIB vs TOLVAPTAN