Porphyria acute: Which Medications Cause It? (1,068 Reports Across 228 Drugs)
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Porphyria acute has been reported as an adverse event with 228 different drugs in the FDA's FAERS database, with 1,068 total reports. 340 of these reports resulted in death.The drugs most commonly associated with Porphyria acute are GIVOSIRAN, RITUXIMAB, and DICLOFENAC.
1,068
Total Reports
228
Drugs Involved
340
Deaths
794
Hospitalizations
41.7 yrs
Average Patient Age
80.2% / 19.8%
Female / Male
Which Drugs Cause Porphyria acute Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| GIVOSIRAN | 381 | 31.1% | 2 | 245 | 1 |
| RITUXIMAB | 265 | 0.2% | 232 | 245 | 229 |
| DICLOFENAC | 262 | 0.3% | 236 | 258 | 254 |
| LEFLUNOMIDE | 249 | 0.4% | 219 | 236 | 235 |
| TOCILIZUMAB | 243 | 0.3% | 219 | 233 | 217 |
| SECUKINUMAB | 241 | 0.2% | 224 | 240 | 241 |
| METHOTREXATE | 238 | 0.1% | 211 | 225 | 226 |
| ACETAMINOPHEN | 237 | 0.2% | 208 | 230 | 226 |
| ADALIMUMAB | 236 | 0.1% | 202 | 224 | 218 |
| PREDNISONE | 227 | 0.1% | 208 | 225 | 223 |
| ALENDRONATE | 225 | 0.8% | 208 | 224 | 225 |
| INFLIXIMAB | 225 | 0.2% | 197 | 220 | 217 |
| CHLORHEXIDINE | 215 | 2.4% | 201 | 214 | 215 |
| PANTOPRAZOLE | 215 | 0.3% | 199 | 214 | 212 |
| FOLIC ACID | 212 | 0.9% | 197 | 211 | 212 |
| HYDROXYCHLOROQUINE | 211 | 0.3% | 194 | 207 | 207 |
| PSEUDOEPHEDRINE | 211 | 1.6% | 192 | 210 | 211 |
| CETIRIZINE | 210 | 0.4% | 191 | 209 | 210 |
| ABATACEPT | 209 | 0.2% | 187 | 208 | 209 |
| ETANERCEPT-SZZS | 208 | 1.8% | 191 | 207 | 208 |