Does TOFACITINIB Cause Spinal fracture? 316 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 316 reports of Spinal fracture have been filed in association with TOFACITINIB (XELJANZ XR). This represents 0.2% of all adverse event reports for TOFACITINIB.
316
Reports of Spinal fracture with TOFACITINIB
0.2%
of all TOFACITINIB reports
14
Deaths
120
Hospitalizations
How Dangerous Is Spinal fracture From TOFACITINIB?
Of the 316 reports, 14 (4.4%) resulted in death, 120 (38.0%) required hospitalization, and 4 (1.3%) were considered life-threatening.
Is Spinal fracture Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOFACITINIB. However, 316 reports have been filed with the FAERS database.
What Other Side Effects Does TOFACITINIB Cause?
Drug ineffective (30,382)
Pain (21,659)
Condition aggravated (16,925)
Arthralgia (15,640)
Fatigue (13,551)
Rheumatoid arthritis (12,277)
Off label use (11,736)
Headache (11,061)
Joint swelling (10,686)
Malaise (9,040)
What Other Drugs Cause Spinal fracture?
DENOSUMAB (2,566)
ADALIMUMAB (827)
LENALIDOMIDE (810)
TERIPARATIDE (527)
ETANERCEPT (420)
PREDNISONE (365)
METHOTREXATE (328)
ZOLEDRONIC ACID (259)
ROMOSOZUMAB-AQQG (256)
TOCILIZUMAB (226)
Which TOFACITINIB Alternatives Have Lower Spinal fracture Risk?
TOFACITINIB vs TOFERSEN
TOFACITINIB vs TOLNAFTATE
TOFACITINIB vs TOLODODEKIN ALFA
TOFACITINIB vs TOLTERODINE
TOFACITINIB vs TOLVAPTAN