Does METHOTREXATE Cause Spinal fracture? 328 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 328 reports of Spinal fracture have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
328
Reports of Spinal fracture with METHOTREXATE
0.1%
of all METHOTREXATE reports
8
Deaths
166
Hospitalizations
How Dangerous Is Spinal fracture From METHOTREXATE?
Of the 328 reports, 8 (2.4%) resulted in death, 166 (50.6%) required hospitalization, and 4 (1.2%) were considered life-threatening.
Is Spinal fracture Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 328 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Spinal fracture?
DENOSUMAB (2,566)
ADALIMUMAB (827)
LENALIDOMIDE (810)
TERIPARATIDE (527)
ETANERCEPT (420)
PREDNISONE (365)
TOFACITINIB (316)
ZOLEDRONIC ACID (259)
ROMOSOZUMAB-AQQG (256)
TOCILIZUMAB (226)
Which METHOTREXATE Alternatives Have Lower Spinal fracture Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA