Does TOLVAPTAN Cause Underdose? 448 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 448 reports of Underdose have been filed in association with TOLVAPTAN (Jynarque). This represents 5.0% of all adverse event reports for TOLVAPTAN.
448
Reports of Underdose with TOLVAPTAN
5.0%
of all TOLVAPTAN reports
117
Deaths
153
Hospitalizations
How Dangerous Is Underdose From TOLVAPTAN?
Of the 448 reports, 117 (26.1%) resulted in death, 153 (34.2%) required hospitalization, and 6 (1.3%) were considered life-threatening.
Is Underdose Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOLVAPTAN. However, 448 reports have been filed with the FAERS database.
What Other Side Effects Does TOLVAPTAN Cause?
Death (800)
Thirst (624)
Off label use (560)
Renal impairment (534)
Product use in unapproved indication (446)
Wrong technique in product usage process (426)
Polyuria (390)
Product dose omission issue (379)
Inappropriate schedule of product administration (376)
Blood creatinine increased (337)
What Other Drugs Cause Underdose?
ADAPALENE (5,192)
AVOBENZONE\OCTISALATE\OCTOCRYLENE (3,722)
INSULIN LISPRO (3,156)
ETANERCEPT (3,145)
GALCANEZUMAB-GNLM (2,909)
ENZALUTAMIDE (2,017)
FLUTICASONE\SALMETEROL (1,600)
ALBUTEROL (1,593)
EXENATIDE (1,571)
TROFINETIDE (1,540)
Which TOLVAPTAN Alternatives Have Lower Underdose Risk?
TOLVAPTAN vs TOPAMAX
TOLVAPTAN vs TOPIRAMATE
TOLVAPTAN vs TOPOTECAN
TOLVAPTAN vs TOPOTECAN\TOPOTECAN
TOLVAPTAN vs TOPROL