Does TOPIRAMATE Cause Arthropathy? 529 Reports in FDA Database

Q: Does TOPIRAMATE cause Arthropathy?

529 reports of Arthropathy have been filed with the FDA for TOPIRAMATE, representing 1.9% of all TOPIRAMATE adverse event reports.

Q: How dangerous is Arthropathy from TOPIRAMATE?

Of 529 reports, 476 (90.0%) resulted in death and 425 required hospitalization.

Grow Your Own Natural Pharmacy at Home

Medicinal Garden Kit — 10 healing herbs, 4,818 seeds + step-by-step guide.

Get the Kit

According to the FDA Adverse Event Reporting System (FAERS), 529 reports of Arthropathy have been filed in association with TOPIRAMATE (Topiramate). This represents 1.9% of all adverse event reports for TOPIRAMATE.

529

Reports of Arthropathy with TOPIRAMATE

1.9%

of all TOPIRAMATE reports

476

Deaths

425

Hospitalizations

How Dangerous Is Arthropathy From TOPIRAMATE?

Of the 529 reports, 476 (90.0%) resulted in death, 425 (80.3%) required hospitalization, and 430 (81.3%) were considered life-threatening.

Is Arthropathy Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for TOPIRAMATE. However, 529 reports have been filed with the FAERS database.

What Other Side Effects Does TOPIRAMATE Cause?

Drug ineffective (5,553) Off label use (4,248) Product use in unapproved indication (2,173) Headache (1,997) Drug intolerance (1,820) Migraine (1,796) Nausea (1,691) Seizure (1,535) Paraesthesia (1,506) Dizziness (1,466)

What Other Drugs Cause Arthropathy?

ETANERCEPT (11,842) ADALIMUMAB (11,670) ABATACEPT (11,099) METHOTREXATE (10,973) TOCILIZUMAB (9,816) LEFLUNOMIDE (9,277) HYDROXYCHLOROQUINE (8,770) RITUXIMAB (8,619) INFLIXIMAB (8,410) SULFASALAZINE (7,545)

Which TOPIRAMATE Alternatives Have Lower Arthropathy Risk?

TOPIRAMATE vs TOPOTECAN TOPIRAMATE vs TOPOTECAN\TOPOTECAN TOPIRAMATE vs TOPROL TOPIRAMATE vs TOREMIFENE TOPIRAMATE vs TORIPALIMAB

TOPIRAMATE Full Profile All Arthropathy Reports All Drugs Causing Arthropathy TOPIRAMATE Demographics