Does TOPIRAMATE Cause Asthenia? 737 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 737 reports of Asthenia have been filed in association with TOPIRAMATE (Topiramate). This represents 2.6% of all adverse event reports for TOPIRAMATE.
737
Reports of Asthenia with TOPIRAMATE
2.6%
of all TOPIRAMATE reports
429
Deaths
447
Hospitalizations
How Dangerous Is Asthenia From TOPIRAMATE?
Of the 737 reports, 429 (58.2%) resulted in death, 447 (60.7%) required hospitalization, and 387 (52.5%) were considered life-threatening.
Is Asthenia Listed in the Official Label?
Yes, Asthenia is listed as a known adverse reaction in the official FDA drug label for TOPIRAMATE.
What Other Side Effects Does TOPIRAMATE Cause?
Drug ineffective (5,553)
Off label use (4,248)
Product use in unapproved indication (2,173)
Headache (1,997)
Drug intolerance (1,820)
Migraine (1,796)
Nausea (1,691)
Seizure (1,535)
Paraesthesia (1,506)
Dizziness (1,466)
What Other Drugs Cause Asthenia?
ADALIMUMAB (9,797)
LENALIDOMIDE (8,192)
METHOTREXATE (6,269)
ETANERCEPT (5,546)
RITUXIMAB (5,489)
PREDNISONE (4,794)
TOCILIZUMAB (3,898)
INFLIXIMAB (3,729)
LEVOTHYROXINE (3,694)
SACUBITRIL\VALSARTAN (3,667)
Which TOPIRAMATE Alternatives Have Lower Asthenia Risk?
TOPIRAMATE vs TOPOTECAN
TOPIRAMATE vs TOPOTECAN\TOPOTECAN
TOPIRAMATE vs TOPROL
TOPIRAMATE vs TOREMIFENE
TOPIRAMATE vs TORIPALIMAB