Does TOPIRAMATE Cause Gene mutation? 38 Reports in FDA Database

Q: Does TOPIRAMATE cause Gene mutation?

38 reports of Gene mutation have been filed with the FDA for TOPIRAMATE, representing 0.1% of all TOPIRAMATE adverse event reports.

Q: How dangerous is Gene mutation from TOPIRAMATE?

Of 38 reports, 34 (89.5%) resulted in death and 27 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 38 reports of Gene mutation have been filed in association with TOPIRAMATE (Topiramate). This represents 0.1% of all adverse event reports for TOPIRAMATE.

Reports of Gene mutation with TOPIRAMATE

0.1%

of all TOPIRAMATE reports

Deaths

Hospitalizations

How Dangerous Is Gene mutation From TOPIRAMATE?

Of the 38 reports, 34 (89.5%) resulted in death, 27 (71.1%) required hospitalization, and 22 (57.9%) were considered life-threatening.

Is Gene mutation Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for TOPIRAMATE. However, 38 reports have been filed with the FAERS database.

What Other Side Effects Does TOPIRAMATE Cause?

Drug ineffective (5,553) Off label use (4,248) Product use in unapproved indication (2,173) Headache (1,997) Drug intolerance (1,820) Migraine (1,796) Nausea (1,691) Seizure (1,535) Paraesthesia (1,506) Dizziness (1,466)

What Other Drugs Cause Gene mutation?

IMATINIB (141) CYCLOPHOSPHAMIDE (139) RITUXIMAB (117) DOXORUBICIN (115) LAMIVUDINE (101) VINCRISTINE (99) PREDNISONE (80) BEVACIZUMAB (71) ETOPOSIDE (66) DASATINIB (63)

Which TOPIRAMATE Alternatives Have Lower Gene mutation Risk?

TOPIRAMATE vs TOPOTECAN TOPIRAMATE vs TOPOTECAN\TOPOTECAN TOPIRAMATE vs TOPROL TOPIRAMATE vs TOREMIFENE TOPIRAMATE vs TORIPALIMAB

TOPIRAMATE Full Profile All Gene mutation Reports All Drugs Causing Gene mutation TOPIRAMATE Demographics