Gene mutation: Which Medications Cause It? (1,720 Reports Across 181 Drugs)
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Gene mutation has been reported as an adverse event with 181 different drugs in the FDA's FAERS database, with 1,720 total reports. 353 of these reports resulted in death.The drugs most commonly associated with Gene mutation are IMATINIB, CYCLOPHOSPHAMIDE, and RITUXIMAB.
1,720
Total Reports
181
Drugs Involved
353
Deaths
291
Hospitalizations
48.8 yrs
Average Patient Age
52.6% / 47.4%
Female / Male
Which Drugs Cause Gene mutation Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| IMATINIB | 141 | 0.3% | 22 | 15 | 8 |
| CYCLOPHOSPHAMIDE | 139 | 0.1% | 78 | 7 | 27 |
| RITUXIMAB | 117 | 0.1% | 72 | 9 | 23 |
| DOXORUBICIN | 115 | 0.1% | 74 | 8 | 25 |
| LAMIVUDINE | 101 | 0.6% | 43 | 6 | 0 |
| VINCRISTINE | 99 | 0.1% | 69 | 4 | 23 |
| PREDNISONE | 80 | 0.1% | 21 | 34 | 5 |
| BEVACIZUMAB | 71 | 0.1% | 18 | 2 | 0 |
| ETOPOSIDE | 66 | 0.1% | 42 | 0 | 18 |
| DASATINIB | 63 | 0.2% | 12 | 5 | 3 |
| CYTARABINE | 62 | 0.1% | 43 | 1 | 15 |
| LEUCOVORIN | 60 | 0.2% | 43 | 3 | 15 |
| ECULIZUMAB | 59 | 0.1% | 3 | 16 | 1 |
| TENOFOVIR DISOPROXIL | 57 | 0.2% | 16 | 1 | 0 |
| METHOTREXATE | 54 | 0.0% | 43 | 1 | 17 |
| NILOTINIB | 54 | 0.2% | 9 | 7 | 5 |
| OSIMERTINIB | 53 | 0.2% | 8 | 5 | 2 |
| PANITUMUMAB | 53 | 0.5% | 18 | 4 | 6 |
| DEXAMETHASONE | 52 | 0.0% | 43 | 28 | 23 |
| FLUDARABINE | 52 | 0.2% | 19 | 1 | 5 |