Does TOPIRAMATE Cause Hepatic enzyme increased? 535 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 535 reports of Hepatic enzyme increased have been filed in association with TOPIRAMATE (Topiramate). This represents 1.9% of all adverse event reports for TOPIRAMATE.
535
Reports of Hepatic enzyme increased with TOPIRAMATE
1.9%
of all TOPIRAMATE reports
464
Deaths
426
Hospitalizations
How Dangerous Is Hepatic enzyme increased From TOPIRAMATE?
Of the 535 reports, 464 (86.7%) resulted in death, 426 (79.6%) required hospitalization, and 418 (78.1%) were considered life-threatening.
Is Hepatic enzyme increased Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOPIRAMATE. However, 535 reports have been filed with the FAERS database.
What Other Side Effects Does TOPIRAMATE Cause?
Drug ineffective (5,553)
Off label use (4,248)
Product use in unapproved indication (2,173)
Headache (1,997)
Drug intolerance (1,820)
Migraine (1,796)
Nausea (1,691)
Seizure (1,535)
Paraesthesia (1,506)
Dizziness (1,466)
What Other Drugs Cause Hepatic enzyme increased?
METHOTREXATE (9,857)
ADALIMUMAB (8,693)
TOCILIZUMAB (7,691)
ETANERCEPT (7,481)
ABATACEPT (7,397)
RITUXIMAB (7,247)
LEFLUNOMIDE (7,173)
INFLIXIMAB (6,778)
HYDROXYCHLOROQUINE (6,555)
TOFACITINIB (6,269)
Which TOPIRAMATE Alternatives Have Lower Hepatic enzyme increased Risk?
TOPIRAMATE vs TOPOTECAN
TOPIRAMATE vs TOPOTECAN\TOPOTECAN
TOPIRAMATE vs TOPROL
TOPIRAMATE vs TOREMIFENE
TOPIRAMATE vs TORIPALIMAB