Does TOPIRAMATE Cause Hypertension? 667 Reports in FDA Database

Q: Does TOPIRAMATE cause Hypertension?

667 reports of Hypertension have been filed with the FDA for TOPIRAMATE, representing 2.3% of all TOPIRAMATE adverse event reports.

Q: How dangerous is Hypertension from TOPIRAMATE?

Of 667 reports, 467 (70.0%) resulted in death and 442 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 667 reports of Hypertension have been filed in association with TOPIRAMATE (Topiramate). This represents 2.3% of all adverse event reports for TOPIRAMATE.

667

Reports of Hypertension with TOPIRAMATE

2.3%

of all TOPIRAMATE reports

467

Deaths

442

Hospitalizations

How Dangerous Is Hypertension From TOPIRAMATE?

Of the 667 reports, 467 (70.0%) resulted in death, 442 (66.3%) required hospitalization, and 420 (63.0%) were considered life-threatening.

Is Hypertension Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for TOPIRAMATE. However, 667 reports have been filed with the FAERS database.

What Other Side Effects Does TOPIRAMATE Cause?

Drug ineffective (5,553) Off label use (4,248) Product use in unapproved indication (2,173) Headache (1,997) Drug intolerance (1,820) Migraine (1,796) Nausea (1,691) Seizure (1,535) Paraesthesia (1,506) Dizziness (1,466)

What Other Drugs Cause Hypertension?

ADALIMUMAB (9,032) METHOTREXATE (7,143) RITUXIMAB (6,760) PREDNISONE (6,087) INFLIXIMAB (5,874) ETANERCEPT (5,677) TOCILIZUMAB (5,492) ABATACEPT (5,114) TOFACITINIB (4,991) ALENDRONATE (4,373)

Which TOPIRAMATE Alternatives Have Lower Hypertension Risk?

TOPIRAMATE vs TOPOTECAN TOPIRAMATE vs TOPOTECAN\TOPOTECAN TOPIRAMATE vs TOPROL TOPIRAMATE vs TOREMIFENE TOPIRAMATE vs TORIPALIMAB

TOPIRAMATE Full Profile All Hypertension Reports All Drugs Causing Hypertension TOPIRAMATE Demographics