Does TOPIRAMATE Cause Irritability? 261 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 261 reports of Irritability have been filed in association with TOPIRAMATE (Topiramate). This represents 0.9% of all adverse event reports for TOPIRAMATE.
261
Reports of Irritability with TOPIRAMATE
0.9%
of all TOPIRAMATE reports
3
Deaths
55
Hospitalizations
How Dangerous Is Irritability From TOPIRAMATE?
Of the 261 reports, 3 (1.1%) resulted in death, 55 (21.1%) required hospitalization, and 16 (6.1%) were considered life-threatening.
Is Irritability Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOPIRAMATE. However, 261 reports have been filed with the FAERS database.
What Other Side Effects Does TOPIRAMATE Cause?
Drug ineffective (5,553)
Off label use (4,248)
Product use in unapproved indication (2,173)
Headache (1,997)
Drug intolerance (1,820)
Migraine (1,796)
Nausea (1,691)
Seizure (1,535)
Paraesthesia (1,506)
Dizziness (1,466)
What Other Drugs Cause Irritability?
DULOXETINE (3,554)
LEVOTHYROXINE (1,692)
LEVETIRACETAM (1,067)
ARIPIPRAZOLE (851)
LEVONORGESTREL (796)
RIBAVIRIN (775)
AMPHETAMINE ASPARTATE\AMPHETAMINE\DEXTROAMPHETAMINE SACCHARATE\DEXTROAMPHETAMINE (745)
PREGABALIN (736)
METHYLPHENIDATE (735)
QUETIAPINE (638)
Which TOPIRAMATE Alternatives Have Lower Irritability Risk?
TOPIRAMATE vs TOPOTECAN
TOPIRAMATE vs TOPOTECAN\TOPOTECAN
TOPIRAMATE vs TOPROL
TOPIRAMATE vs TOREMIFENE
TOPIRAMATE vs TORIPALIMAB